Teams of prominent scientists and ethicists have called for the end of medically unnecessary nonconsensual surgeries on intersex children in two new papers.
On the heels of the United Nations Human Rights Council’s first-ever resolution affirming the rights of intersex people, the papers signal growing international resolve to address rights violations experienced by people born with variations in their sex characteristics, sometimes called intersex traits.
Since the 1950s, surgeons have conducted irreversible and medically unnecessary “normalizing” operations on intersex children, such as procedures to reduce the size of the clitoris, which can result in scarring, sterilization, and psychological trauma. Intersex advocacy groups, as well as various medical and human rights organizations, have spoken out against these surgeries for decades. Despite a growingconsensus that these surgeries should end, as well as global progress on banningthem, some parents still face pressure from surgeons to choose these operations for children too young to participate in the decision.
The authors of one of the expert papers found that surgeons’ subjective cosmetic preferences for the appearance of genitals was one of the most commonly reported justifications in the paper’s sampling of elective “normalizing” surgeries on children younger than 10. Cosmetic appearance of genitals has no validated measure, so the data featured surgeons’ subjective descriptions instead. The authors, including five World Health Organization staff members, concluded that, “Legislating and medical regulatory bodies should advocate for ending the conduct of irreversible, elective, ‘sex-normalizing’ interventions conducted without the full, free and informed consent of the person concerned.”
The second paper, co-signed by dozens of professionals around the world, including physicians, ethicists, and psychologists, examined the ethical implications of “normalizing” interventions on children’s genitals. The authors conclude that clinicians “should not be permitted to perform any nonvoluntary genital cutting or surgery on any child, regardless of the child’s sex traits or socially assigned gender, unless doing so is urgently necessary to protect the child’s physical health.”
Both papers advocate that children born perfectly healthy – just a little different – should be free to grow up and make decisions about their own bodies.
PinkNews examines the issues faced by bisexual people at work, the impact of bi-erasure and what colleagues and employers alike can do to support their bisexual colleagues.
A common experience for many bisexual people is the feeling of being invisible, and this rings true for the workplace. Many bisexual people are faced with the choice of being out and living their authentic selves or trying ‘fit in’.
With the amount of time spent at work, having to hide a huge part of one’s identity can be emotionally draining and can lead to burnout, mental health issues and even exacerbate imposter syndrome.
LGBTQ+ people are often discriminated against and even bullied at work: Data from McKinsey suggests that up to 30 per cent of LGBTQ+ people believe that their sexual identity will harm their career progression.
Katherine, an art history professor at a small state university in the rural US Midwest, believes her bisexual identity has positively impacted her career in academia – but she remains acutely aware of the issues it poses, too.
The bisexual Pride flag. (Getty)
She tells PinkNews: “While working in a Women’s and Gender Studies department for five years, in a way [being bisexual] legitimises my research and teaching interests. When introducing myself to students in those classes, it creates a safe space for my LGBTQ+ students to share their experiences and perspectives.”
However, living in a largely conservative part of the country and with anti-LGBTQ+ bills on the rise, Katherine still maintains a level of care in how she discloses her sexual identity.
“I mostly have fear from outside the university setting from internet trolls and conservative politicians,” she explains. “But this is also one of the reasons I try to be so open with students. So many of them come from rural communities where they can’t explore their own sexuality or gender.”
The impact of bisexual erasure at work
Many in the bisexual community contend with bi-erasure – the tendency to remove, ignore and even falsify experiences of bisexuality in legacy media, academia and history. In its most extreme form, bi-erasure can also manifest as the belief that bisexuality doesn’t exist.
Bisexual people can experience specific micro-aggressions at work, including assumptions about their partners and relationships and inappropriate questions about their personal lives. Bisexual women are often fetishised and bisexual men are often told that they are “too afraid to come out as gay.”
Frustratingly for the bi community is that sometimes bi-erasure and micro-aggressions come from within the LGBTQ+ community itself.
Fears of experiencing this could be preventing bi people from being out at work. Data from Catalyst found that in the US, just 17.5 per cent of bisexual men are out at work, compared to 50 per cent of gay men. For bisexual women, nearly 20 per cent are out compared to 49 per cent of lesbians.
Katherine admits that bi-erasure does happen frequently: “People tend to view any monogamous relationship, regardless of the gender of those involved, as being straight or gay.”
She says she combats bi-erasure by being more open with friends and family, yet she does acknowledge the negative impact it can cause.
“I think the bi-erasure affects me in the way that it is part of me, and I hate that in some cases I cannot share that part of me for fear of being targeted politically.”
Supporting bisexual colleagues and employees at work
Here in the UK, the most recent census data reveals that 1.28 per cent of the population (640,000) identified themselves as bisexual. For Gen Z specifically, those born between 1997 and 2012, four per cent identified themselves as bi.
As the younger generations feel more comfortable being out and head into the workplace, the responsibility of employers and colleagues to recognise all facets of the LGBTQ+ community is even more crucial.
Aside from simple steps like respecting pronouns and challenging bullying and discrimination, there are some other things business leaders and co-workers can do to support the ‘B’ in the LGBTQ+.
Education
Bisexuality is often misunderstood and can be attached to stereotypes. If employers understand that being bisexual is a valid sexual orientation, and that the sex of an employee’s partner, partners or spouse does not immediately categorise them as ‘gay’ or ‘straight’, it can create an empathetic working environment where everyone has the opportunity to live their authentic lives while at work. Business leaders should consider targeted training and resources that specifically tackle the bi-experience.
Listening and communication
Active listening is a powerful tool for supporting bisexual employees. Much like the rest of the LGBTQ+ community, no two peoples experiences are the same. Creating opportunities for open conversations where bisexual employees can share their experiences, concerns, and suggestions. Be empathetic and validate their feelings, showing that you genuinely care about their well-being. Encourage a culture of respectful communication, where everyone’s perspectives are valued.
Respect privacy and the ‘coming out’ experience
Coming out is a personal journey, and it’s important not to pressure anyone to disclose their sexual orientation. Never assume someone’s sexual orientation or share their personal information without their consent. Part of an inclusive workplace is creating a safe space where employees can choose to share when they’re ready promotes trust and respect.
The two men who provided the narcotics that caused the death of trailblazing trans activist and actress Cecilia Gentili have both pleaded guilty to distributing the drugs.
Gentili, 52, died in her Brooklyn apartment from fentanyl-laced heroin that authorities say she received from the men, Michael Kuilan, 44, and Antonio Venti, 52.
Prosecutors said Gentili was found dead in her bedroom in February from the combined effects of controlled substances including fentanyl, xylazine (a vetrinary sedative), cocaine and heroin. The heroin, laced with fentanyl, was provided by Kuilan and Venti.
On Monday, Kuilan on Monday pleaded guilty to possession and possession with intent to distribute both of the drugs, according to a statement from the U.S. attorney’s office for the Eastern District of New York. Kuilan also pleaded guilty to a charge of gun possession following an earlier conviction that barred him from carrying a firearm.
Venti pleaded guilty to narcotics possession in July.
Text messages, cell site data, and other evidence revealed that Venti sold the fentanyl and heroin mixture to Gentili on February 5, 2024, and that Kuilan supplied Venti with the lethal narcotics.
As part of their plea agreements, Kuilan and Venti agreed that they caused Gentili’s death. In addition, law enforcement searched an apartment in Williamsburg, Brooklyn belonging to Kuilan and found hundreds of baggies of fentanyl, as well as a handgun and ammunition.
“The perpetrators of the tragic poisoning of Cecilia Gentili, a prominent leader of the New York transgender community, have now both admitted their guilt in selling the lethal drugs that have caused this heartbreaking death,” said U.S. Attorney Breon Peace. “These drugs, heroin and fentanyl, have caused so much pain throughout our community. I hope this case will bring a sense of closure to Gentili’s family and serve as a warning that this Office will be relentless in holding fentanyl dealers accountable.”
“While these guilty pleas can’t undo the tragic loss,” Peace added, “it sends a message that we will do everything we can to make sure those responsible for drug related deaths face the consequences for their actions, and the families of those who lost their lives receive justice.”
Gentili’s death shocked the transgender community in New York, where she received an outpouring of grief from local prominent figures, including nightlife legend Amanda Lepore and Rep. Alexandria Ocasio-Cortez (D-NY), as well as her fellow cast members on the trans-centered TV series Pose.
The Argentina native was honored with a memorial service at St. Patrick’s Cathedral in Manhattan, attended by over a thousand mourners. The joyous and “scandalous” service earned condemnation from the Roman Catholic Archdiocese of New York City.
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Daniel Trujillo first spoke at a hearing at the Arizona legislature when he was nine years old. The now-17-year-old has spent years telling lawmakers that as a trans boy he exists, he is loved, and he’s thriving.
In fact, at one drive home after a hearing, Daniel told his mother Lizette that the only time he felt discriminated against was when he would go to those meetings. Outside of facing down anti-trans lawmakers, he lived a normal teenage life. He skateboarded. He hung out with friends. He was happy.
Daniel is content to share his story. It’s kind of his way of giving back.
“There’s a lot of younger trans kids [out there who] are shy, and they don’t always have the words to express the feelings that we all feel,” he told The Advocate. “And so sometimes it feels like this is the least I can do for these people that are so close to me.”
Daniel’s and others’ joy is at the center of a new campaign from the American Civil Liberties Union called “Freedom to Be.” As the organization tracks hundreds of bills going after transgender people, like Daniel, the group is pushing back by highlighting the actual lives these individuals lead.
The campaign couldn’t come at a more important time. The Skrmetti Supreme Court case could affirm Tennesse’s ban on gender-affirming care, eroding the medically necessary care that many trans youth depend on.
Freedom to Be will be a year-long, multimedia, multi-platform campaign, with a focus on long- and short-form video content, including a portrait series of trans people, digital and billboard ads, art installations created by and for trans people that will blanket the National Mall in 2025, and call to action surrounding a pledge to support trans youth, the ACLU said.
Abdool Corlette conceptualized Freedom to Be.
“We knew that we wanted to create something bold, something bright, something that embodies the like beautiful simplicity of the words “Freedom to be,” “Freedom to be me,” said Corlette, the head of brand at ACLU. “[The campaign] is about bringing as many people in. We knew that we wanted to create beautiful portraits of our primary storytellers that captured them as they are, that captured them in the beauty of their day-to-day lives.”
Corlette added that the team wanted to put power back into the hands of the trans storytellers. They asked them what comes to mind when they think of freedom to be me. What does that provoke in you? What does that inspire in you?
“We really allowed the answers from our storytellers to inform the look and feel of the campaign. We wanted this campaign to feel accessible. We wanted it to feel like we were just observing a person’s everyday life,” Corlette said. “We knew that there was already so much rich authenticity in folks’ day-to-day lives, and we just wanted to bring that to a wider audience.”
The focus on joy, Corlette said, is just continuing the legacy of LGBTQ+ rights movements. Trans and queer liberation always centered joy as a core element of the battle against injustice.
“What trans folks know is that their lived experience should not be defined by the people who are trying to erase them. And joy is something that is key to the trans experience. There is nothing more powerful than experiencing joy in the face of so much oppression, and we need it now more than ever. We need to showcase narratives that are not just rooted in trauma,” Corlette said. “There is nothing more powerful than saying, ‘I deserve the freedom to be.’”
New research suggests bisexual men experience body dissatisfaction differently from gay men.
Bi men are reportedly less motivated to be lean and show a lower dissatisfaction rate with their muscularity, while gay men show a higher drive, according to psychologists at Nottingham Trent University (NTU), in the UK.
After interviewing more than 370 gay, bisexual and straight cisgender white men as part of a study on body satisfaction, the study showed that men who identify as bi are more likely to have the same sort of opinions about body satisfaction as straight men.
However, results for other concerns, including height, penis size and capability, remained consistent among all sexual orientations.
The study, “Tackling bisexual erasure: An explorative comparison of bisexual, gay and straight cisgender men’s body image” was published in an effort to tackle the “homogenous” way that gay and bi men are grouped in research.
New research has shown why bisexual men should not be grouped with gay men when it comes to body image. (Getty)
Dr Liam Cahill, the project’s lead researcher and a lecturer in LGBTQ+ psychology at NTU, said the traditional act of grouping bisexual and gay men is outdated.
“Traditionally, bisexual men have been grouped in the same category as gay men when it comes to body image research,” he said. “Our findings show they are unique in how they experience differences in their body image.”
While society generally has a preference for men to be “muscular or lean with low body fat,” bisexual men’s dissatisfaction with their physique is only compounded when integrating with the gay community, he added.
However, the study’s results still suggest that, while bisexual and straight men are less dissatisfied with their muscularity, societal pressures still influence all men – regardless of sexuality.
“When it comes to increased pressure and dissatisfaction related to muscularity, previous studies have found that gay men’s stronger preference for muscular partners may contribute to their higher levels,” Cahill said. “This is a pressure that bisexual men may only experience when they are integrated with the gay community, hence their dissatisfaction is lower.”
This means that bi, straight and gay men all experience the same motivation to gain muscle and lose body fat, but gay men are typically more dissatisfied with the results.
“The experiences of bisexual men are often overlooked in research,” the study concluded. “Bisexual people experience greater stigma, marginalisation and prejudice than other sexual [minority] identities.
“As of the most recent review of this issue, only a small number of studies have explored bisexual and gay men’s body image differences.
“Our findings contradict the view that bisexual and gay men experience similar body-image concerns concerning their drive for leanness and muscularity dissatisfaction.”
Brands that are supportive of LGBTQ+ rights or social justice movements see greater consumer engagement and loyalty from customers, a new study found. The study comes after several major brands have distanced themselves from their previous pro-diversity initiatives.
Unstereotype Alliance, a business initiative convened by UN Women, more inclusive advertising campaigns positively impact profits, sales, and brand worth.
Researchers at Saïd Business School at Oxford University analyzed data from Diageo, Kantar, and Unilever in collaboration with the Geena Davis Institute. The research, based on an analysis of 392 brands across 58 countries, reveals that inclusive advertising can boost short-term sales by nearly 3.5% and drive long-term sales by over 16%.
The study spanned various product categories, including confectionery, snacks, personal care, beauty, pet food, pet care, alcohol, consumer healthcare, and household products across diverse regions.
Inclusive advertising also persuades 62% of consumers to choose a product and enhances brand loyalty for 15% of shoppers. The study highlights that ads that authentically portray people without using stereotypes have a clear competitive advantage in the marketplace, influencing consumer preferences and long-term success.
Sara Denby, head of the Unstereotype Alliance secretariat at UN Women, emphasized that the long-held belief that inclusive advertising could harm a business – or, in conservative parlance, “Go woke, go broke” – has hindered progress for too long. “This claim is consistently unfounded,” she said, “but we needed evidence to counter it. These undeniable findings should reassure any business and motivate brands to strengthen their commitment to inclusivity—not only to serve their communities but also to drive growth and boost profitability.”
Unstereotype Alliance was founded in 2017 and has 240 member companies. The organization seeks to end harmful stereotypes in advertising and has 12 national chapters across five continents.
In the effort to be more inclusive, some companies have fumbled. Kendall Jenner and Pepsi were ridiculed after an ad from the soda company showed Jenner solving a clash between protestors and the police by handing a cop a soft drink.
On the other side, the beer brand Bud Light also faced right-wing rage after partnering with trans influencer Dylan Mulvaney. After the incident, Jason Warner, CEO of the European branch of Bud Light’s parent company, Anheuser-Busch InBev, said that the company would no longer attempt inclusivity and “stay in our lane.”
The study comes after right-wing influencer Robby Starbuck pressured multiple companies to cave by accusing them of having “woke agendas” and sending a social media mob after them. Starbuck succeeded in getting companies such as Lowe’s, John Deere, Harley Davidson, and more to drop their DEI initiatives, stop partnering with the Human Rights Campaign, and end sponsorship of Pride festivals. When fear of Starbuck caused Ford Motors to follow behind the other brands, president of the Human Rights Campaign, Kelley Robinson, called Starbuck a “MAGA bully and Republican-reject.”
It later released a study that details how rollbacks on DEI from large corporations in recent years are wildly unpopular with LGBTQ+ individuals and alienating many consumers. The latest research adds even more weight to that argument.
GLAAD is calling on Meta, the parent company of Instagram, Facebook, and WhatsApp, to take stronger action against anti-transgender content, submitting a public statement to Meta’s Oversight Board that urges the company to enforce its policies on hate speech and bullying.
The advocacy group’s involvement comes as the Oversight Board reviews two cases in which Meta failed to remove videos from Facebook and Instagram that misgendered transgender people despite being flagged multiple times for violating the platform’s policies.
Senior director of GLAAD’s Social Media Safety Program, Jenni Olson, told The Advocate in a statement that Meta must follow its existing guidelines.
“Meta’s Bullying and Harassment policy clearly states that users are ‘protected from … Claims about romantic involvement, sexual orientation or gender identity.’ By intentionally misgendering these two trans people, the two videos in this case are making a ‘claim about a person’s gender identity.’ It’s very clear that the company should enforce its own policies and mitigate the posts accordingly,” Olson said.
The cases in question involve one video on Facebook showing a confrontation between a woman and a transgender woman in a public restroom and another on Instagram of a transgender girl participating in a sporting event where her gender identity is challenged. Both posts received thousands of views, but Meta opted not to take them down, ruling that the content did not violate its Hate Speech or Bullying and Harassment Community Standards. Misgendering, referring to someone using incorrect pronouns or gendered language, is not explicitly considered a violation under Meta’s hate speech policies.
Olson pointed out that Meta’s inaction perpetuates harm against transgender users.
“Meta’s failure to enforce its own policies continues to cause immense harm, and we look forward to the ruling of the Oversight Board on this case,” she noted.
GLAAD’s public comments to the Oversight Board highlighted how both videos should have been removed under Meta’s current guidelines. Regarding the Instagram post, which misgendered a transgender athlete, GLAAD pointed out that Meta’s own Bullying and Harassment policy states that users are protected from claims about their gender identity. The video, they argue, clearly violates this standard. GLAAD wrote, “Clearly, this policy is applicable to cover targeted misgendering (as well as targeted deadnaming) — which is a ‘claim about a person’s gender identity.’ Specifically here, the account denies the minor’s gender identity by asserting that she is a boy.”
In the Facebook case, where a transgender woman was misgendered in a restroom confrontation, GLAAD again emphasized that Meta’s policies regarding claims about gender identity should have applied. GLAAD’s statement said the post “intentionally misgendered” the woman and should have been removed under the company’s Bullying and Harassment guidelines.
GLAAD’s critiques build on previous rulings by the Oversight Board that have faulted Meta for failing to enforce its policies onLGBTQ+ hate speech. In a January 2024 decision involving an anti-trans post in Polish, the Oversight Board ruled that “the fundamental issue in this case is not with the policies, but their enforcement,” concluding that Meta had repeatedly failed to take appropriate action.
GLAAD publicly criticized Meta following the company’s independent Oversight Board’s ruling on a post from Poland, where a user shared content implying that transgender people should die by suicide. Despite multiple reports from users, Meta initially left the post up, claiming it didn’t violate the company’s Hate Speech and Suicide and Self-Injury Community Standards. The post was only removed after the Oversight Board selected it for review and ultimately overruled Meta’s decision.
Sarah Kate Ellis, president and CEO of GLAAD, responded at the time by calling on Meta CEO Mark Zuckerberg to publicly address the company’s failings in protecting transgender people from hate speech and harassment. Ellis emphasized the urgency for Meta to demonstrate that it prioritizes the safety and dignity of LGBTQ+ users. Meta has defended its decision to leave the posts up, citing the broader social and political debate around transgender issues, including restroom access and sports participation. The company argued that these discussions are part of public discourse and should be protected under its “newsworthiness allowance,” even if the content misgenders individuals. However, GLAAD contends that such debates should not rely on dehumanizing rhetoric or misinformation.
The Oversight Board’s ruling on these cases is expected in the coming months. While its decisions are not binding, Meta must respond and take action based on the board’s recommendations.
Olson reiterated that protecting LGBTQ+ users must be more than a promise on paper.
“In previous rulings on Meta’s moderation of anti-LGBTQ content, the Oversight Board has repeatedly criticized Meta’s failures to enforce its own hate speech policies,” Olson said. “This reflects the daily experience of so many LGBTQ users on Instagram, Facebook, and Threads — which over time seems to indicate that protecting LGBTQ users is simply not a priority for the company.”
Meta did not respond to The Advocate’s request for comment.
The hotly anticipated results are in from a landmark pair of major clinical trials of a long-acting, injectable HIV-prevention drug that only requires dosing every six months.
They are sensational.
Thrilled over the news Thursday that lenacapavir was 89% more effective at preventing HIV than daily oral preventive medication among gay, bisexual and transgender people, plus previous news that the injectable drug was 100% effective in cisgender women, HIV advocates are looking to the future. They hope that if rolled out broadly and equitably, lenacapavir could be the game changer the nation badly needs.
“These kinds of results are unprecedented,” said Dr. Jared Baeten, senior vice president of virology clinical development at Gilead Sciences, which manufactures lenacapavir. “I have moments like this where I truly am speechless. What this can mean for the trajectory of the HIV epidemic is everything that all the world has imagined for years. We can actually turn off new infections.”
And yet, as battle-worn public health advocates stand on the front lines of an over four-decade effort to finally bring the U.S. HIV epidemic to heel, they find a cold, hard fact staring back at them: Lenacapavir is extraordinarily expensive.
Calling lenacapavir’s clinical trial results “nothing short of amazing,” Jen Kates, director of global health and HIV policy at the nonpartisan health nonprofit KFF, said the news “raises the stakes on the importance of getting this new tool to all those who need it, in the United States and around the world. The track record thus far has unfortunately not been a good one.”
Gilead also manufactures Truvada and Descovy, the two daily oral tablets approved for use as pre-exposure prophylaxis, or PrEP. The pharma giant has already secured approval for the injectable drug in treating highly drug-resistant HIV.
Lenacapavir’s current list price for use as HIV treatment is $3,450 per month. Gilead has not yet indicated whether it will set a different price for the drug’s use as PrEP. A company spokesperson told NBC News on Thursday, however, that the reference point for the price of lenacapavir as PrEP will not be its current use as treatment. It remains unclear whether that statement signals a willingness on the part of the pharmaceutical giant to bring the injectable drug’s price down closer to Earth for its use as HIV prevention.
Given that Truvada has been available as a generic since 2020 and now costs as little as $20 per month (Descovy remains on patent and has a $2,200 sticker price), it remains unclear whether, absent some perhaps novel form of government intervention, insurers will indeed make lenacapavir available widely enough to have what epidemiologists predict could be a sweeping public health impact.
Gilead plans to submit lenacapavir for approval for use as PrEP to the Food and Drug Administration by the end of the year. So this powerful new HIV-prevention tool could hit the U.S. market by mid-to-late 2025.
An HIV-prevention upgrade is badly needed. Since Truvada was approved as the first form of PrEP 12 years ago, the drug has failed to achieve anything in the U.S. approaching its awesome impact on HIV rates among gay and bisexual men in wealthy Western nations such as Australia and the United Kingdom. Those countries boast the type of streamlined sexual-health-care systems that the fragmented U.S. health care system lacks.
“The entire story of PrEP is a missed opportunity,” said Amy Killelea, a health consultant in Arlington, Virginia, and a prominent HIV advocate.
Unprecedented clinical trial results
The advanced clinical trial of lenacapavir in gay men was launched in 2021 at 88 sites across the U.S. and Latin America, and in South Africa and Thailand. It enrolled more than 3,250 cisgender men and transgender and nonbinary people who have sex with male partners.
The participants were randomized to receive either lenacapavir or Truvada on a placebo-controlled, double-blind basis, meaning neither the participants nor the researchers knew who was getting which drug. They were instructed to return every six months for an injection and to take the one dose of the provided pills daily.
A planned interim independent analysis of the trial results indicated that two out of 2,180 participants who received lenacapavir contracted HIV during the trial, as did nine out of 1,087 people who got Truvada. For the lenacapavir group, this represented an 89% lower HIV rate than those in the Truvada group and what Gilead estimated was a 96% lower infection rate than would be expected absent either drug.
Given the clear statistical superiority of lenacapavir over Truvada, the trial’s blinded phase will now be ended several months early. The participants will be informed of which drug they received and provided the option of receiving either going forward.
Lenacapavir proved safe and well-tolerated, with no major safety concerns, according to Gilead. One catch is that the subcutaneous, or under the skin, injection of the drug in the abdominal area leaves a small deposit that can be visible among those with low body fat. It is possible that in real-world use, some will find this off-putting or stigmatizing.
When taken as prescribed, Truvada is over 99% effective at preventing HIV; Descovy is comparably effective. But poor adherence to the daily oral PrEP regimen compromises oral PrEP’s efficacy. And gay and bisexual Black men in particular — the group with the highest HIV rate — have often posted particularly low adherence rates in oral PrEP studies.
The Centers for Disease Control and Prevention estimated in May that between 2018 and 2022, annual U.S. HIV transmissions declined by a modest 12%, from 36,200 to 31,800 cases. Approximately 7 in 10 new HIV cases are in gay and bisexual men, with Black people and Latinos in this group acquiring the virus at much higher rates than their white counterparts. Transgender women, in particular those of color, are also at substantial risk of the virus.
A problem that has bedeviled the CDC and HIV advocates for over a decade is that, in particular given the disproportionately high rates of the virus in their respective demographic groups, Black and Latino gay and bisexual men have never adopted PrEP use at the critical mass needed to truly bring the U.S. epidemic to heel among them. Meanwhile, PrEP has accelerated a long-standing decline in HIV among their white counterparts, exacerbating the gap between the groups.
HIV advocates worry that lenacapavir could only widen such racial disparities further.
“Oral PrEP has been around since 2012. Look at our failure,” said Jirair Ratevosian, an associate research scientist at the Yale School of Nursing.“How do we learn from the past so we don’t squander the opportunity?”
Excitement about lenacapavir’s potential
Dr. Hansel Tookes, a professor in the infectious diseases division at the University of Miami Miller School of Medicine, was the most bullish HIV expert to speak with NBC News about lenacapavir’s prospects.
“I am borderline delusional,” Tookes said of his excitement about how lenacapavir could benefit, in particular, the Southern gay men of color he’s charged with helping protect from HIV.
The South, where the effort to treat and prevent HIV remains hampered by the refusal by seven of 11 states to expand Medicaid under the Affordable Care Act, accounts for half of all new HIV cases, according to the CDC.
“Right now, the challenge is having people take a pill every day to prevent something that they don’t have,” said Tookes of the difficulty of engaging young people in particular in such a banal, forward-thinking routine. “Having to get an injection twice a year is an easier sell.”
Dr. Boghuma Titanji, an infectious disease specialist at Emory University, said she frequently sees new HIV diagnoses in Atlanta, where her university is based, especially among young Black and Latino men who have sex with men.
“These groups often lack access to and information about existing PrEP options,” she said. “While lenacapavir is a valuable addition to our toolkit, for it to reach its full potential, it must be made accessible to those who stand to benefit the most from its effectiveness.”
After Gilead released its initial findings in June from an advanced clinical trial of lenacapavir in cisgender women and adolescent girls in sub-Saharan Africa, HIV advocates immediately put pressure on Gilead to provide the drug at a scalable cost to lower-income nations. This chorus is sure to get louder now that lenacapavir is officially highly effective at protecting gay and bisexual men and trans people as well. Still to come are results from ongoing clinical trials of the drug in people who inject drugs and cisgender women in the U.S.
On Thursday, Gilead stated in a release that the company is committed to delivering “lenacapavir swiftly, sustainably and in sufficient volumes, if approved, to high-incidence, resource-limited countries, which are primarily low- and lower-middle-income countries.” The company is in “active discussions with the HIV community” about these plans.
“It’s not progress if lenacapavir’s cost and other structural challenges impede access, domestically or globally,” said Tim Horn, director of medication access at the public health nonprofit NASTAD. “The results of the drug’s clinical trials, he said, “must be to the benefit of all people at risk for HIV, including those with cost-related hurdles to state-of-the-art prevention and care.”
CORRECTION (Sept. 12, 2024, 3:15 p.m. ET): A previous version of this article misstated the monthly sticker price of ViiV Healthcare’s injectable drug Apretude. It’s $1,965 monthly, not $3,930. The price per injection, which is administered every two months, is $3,930.
With his selection by Vice President Kamala Harris, Minnesota Governor Tim Walz could be the next Vice President of the United States. Walz’s record of support for LGBTQIA2S+ youth and adults has been clear throughout his career as a teacher, legislator, and Governor.
Under Minnesota’s pro-equality legislative and executive branches, Governor Walz, Lt. Governor Flanagan, and the Queer Legislators Caucus built the state into a national model for protecting the healthcare access and human rights of the 2SLGBTQIA+ communities, especially transgender, non-binary and 2-Spirit residents.
Below are a few of the accomplishments in Minnesota in the 2023-2024 legislative biennium.
First Queer Caucus: Voters elected 11 new LGBTQ+ individuals to the MN Legislature in 2022. In December 2022, Representative Leigh Finke was selected as the inaugural chair of the Queer Legislators Caucus in Minnesota.
Trans Refuge State: Gov. Walz signed an executive order to protect those traveling to Minnesota to receive gender-affirming care. Two months later Trans Refuge became the law in Minnesota, protecting patients, families, and providers from out-of-state laws punishing trans health care access, as well as allowing Minnesota courts to hear cases in which parents disagree about health care planning.
The Take Pride Act expanded protections under the Minnesota Human Rights Act for trans and queer Minnesotans by updating language around gender identity and sexual orientation. The bill also banned rental discrimination in duplexes for LGBTQ renters, as well as banning discriminatory hiring practices in certain nonprofit organizations.
Banned Panic Defense: The panic defense is a legal strategy in which defendants charged with violent crimes attempt to avoid liability due to the real or perceived sexual orientation or gender identity of the victim.
Menstrual Equity: All menstruating students in grades 4-12 are provided free period products in Minnesota schools. These products will be available to all students regardless of gender. The law does not specify which bathrooms the products must be in, it requires school districts to develop plans to ensure all students who menstruate can access the products for free.
This is only a PORTION of what Minnesota accomplished. Other wins include:
Walz and the pro-equality majority legislature also passed and signed into law additional measures for the safety, health and wellbeing of all Minnesotans and youth:
The US Supreme Court has agreed to hear a legal challenge to a Tennessee banon trans healthcare.
The bill, approved by state lawmakers last year, mimics similar laws in other states, with civil penalties for any adult who aids a minor to receive getting out-of-state gender-affirming care without their parent’s consent.
Several families, backed by the American Civil Liberties Union (ACLU) sued Tennessee to prevent the bill passing into law.
The case will now be heard by the country’s top court in October.
The ACLU’s deputy director for trans justice, Chase Strangio, said: “The future of countless transgender youth in this and future generations rests on this court adhering to the facts, the constitution and its own modern precedent.
“These bans represent a dangerous and discriminatory affront to the well-being of transgender youth across the country and their constitutional right to equal protection under the law. They are the result of an openly political effort to wage war on a marginalised group and our most fundamental freedoms.”
Following the Supreme Court’s decision to take the case, 64 trans adults, including actor Elliot Page, filed a brief sharing their own experiences.
What is the Supreme Court case US v Skrmetti?
Following the passing of the bill in the state house of representatives and senate, the ACLU, and Lambda Legal, aided by lawyers from Akin Gump Strauss Hauer & Feld, sued Tennessee.
The pushback was, to a large degree, over the bill’s aim to outlaw medical care for trans youngsters up to the age of 18, while those currently receiving gender-affirming care would have been forced to end it by July 2023.
Samantha Williams, from Nashville, who brought the case on behalf of her trans 15-year-old daughter, said it was “incredibly painful” to watch her child suffer as a consequence of the proposed legislation.
“We have a confident, happy daughter now, who is free to be herself and she is thriving,” Williams said. “I am so afraid of what this law will mean for her.”
In June 2023, a federal judge blocked the bill from going forward. But a federal appeal court overturned that decision last September, allowing the bill to go into effect, a decision the ACLU described as “beyond disappointing.”
In June this year, the Supreme Court agreed to hear the case. While the outcome will specifically affect the Tennessee bill, it is likely to set a legal precedent for similar laws in other states.
Data collected and shared by the ACLU found that at least 530 anti-LGBTQ+ bills have been proposed in the US since the beginning of the year, with 112 of those being healthcare restrictions.
Lambda Legal senior lawyer Tara Borelli said: “This court has historically rejected efforts to uphold discriminatory laws. Without similar action here, these punitive, categorical bans on the provision of gender-affirming care will continue to wreak havoc on the lives of transgender youth and their families.”
